منابع مشابه
Treatment as prevention--a double hat-trick.
208 www.thelancet.com Vol 378 July 16, 2011 4 Family Health International. FHI statement on the FEM-PrEP HIV prevention study. http://minilicious.wordpress.com/2011/04/18/fh i-statement-onthe-fem-prep-hiv-prevention-study/ (accessed June 28, 2011). 5 Abdool Karim SS, Kashuba A, Werner L, Abdool Karim Q. Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implicat...
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The RNA-processing protein TDP-43 is central to the pathogenesis of amyotrophic lateral sclerosis (ALS), the most common adult-onset motor neuron (MN) disease. TDP-43 is conserved in Drosophila, where it has been the topic of considerable study, but how TDP-43 mutations lead to age-dependent neurodegeneration is unclear and most approaches have not directly examined changes in MN morphology wit...
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Chromatin-remodeling proteins have a profound role in the transcriptional regulation of gene expression during development. Here, we have shown that the chromodomain-containing protein Hat-trick is predominantly expressed within the oocyte nucleus, specifically within the heterochromatinized karyosome, and that a mild expression is observed in follicle cells. Colocalization of Hat-trick with He...
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One person’s fight against an HIV infection can decrease the virus’s ability to threaten its next victim, say Goepfert et al. (page 1009). Mutations that help the virus survive in one host decrease its ability to replicate in the next. HIV mutations that help the virus bypass the host’s immune system often fall within gag. This gene is a favorite target for mutations because, for some reason, G...
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ژورنال
عنوان ژورنال: Immunity
سال: 2019
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2019.08.018